What is Naegleria fowleri?

South Korea reported its first case of infection from Naegleria fowleri or “brain-eating amoeba”. A 50-year-old Korean national, who had recently returned from Thailand, died 10 days after showing symptoms of the rare yet fatal infection.

What is Naegleria fowleri?

  • Naegleria is an amoeba, a single-celled organism, and only one of its species, called Naegleria fowleri, can infect humans.
  • It was first discovered in Australia in 1965 and is commonly found in warm freshwater bodies, such as hot springs, rivers and lakes.
  • The amoeba enters the human body through the nose and then travels up to the brain. This can usually happen when someone goes for a swim, or dive or even when they dip their head in a freshwater body.
  • In some cases, it was found that people got infected when they cleaned their nostrils with contaminated water.
  • Scientists haven’t found any evidence of the spreading of Naegleria fowleri through water vapour or aerosol droplets.
  • Once Naegleria fowleri goes to the brain, it destroys brain tissues and causes a dangerous infection known as primary amebic meningoencephalitis (PAM).
  • The first signs of PAM start showing within one to 12 days after the infection.
  • In the initial stages, they might be similar to symptoms of meningitis, which are headache, nausea and fever. In the later stages, one can suffer from a stiff neck, seizures, hallucinations, and even coma.
  • The fatality of PAM is as such that only four people have survived out of 154 known infected individuals in the United States from 1962 to 2021.
  • As the Naegleria fowleri infection is rare and progresses quickly, scientists haven’t been able to identify any effective treatments yet.
  • At present, doctors treat it with a combination of drugs, including amphotericin B, azithromycin, fluconazole, rifampin, miltefosine, and dexamethasone.

(Source: Indian Express)

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