What is ‘Manathakkali’?

Kerala’s ‘Manathakkali’ (Black nightshade or Solanum nigrum), a berry-bearing shrub found in the backyard, is traditionally known for its medicinal value.

  • The United States Food and Drug Administration (FDA) has noticed the potential of a compound isolated from the plant to treat liver cancer, thanks to the findings of a team of scientists at Rajiv Gandhi Centre for Biotechnology (RGCB).
  • According to the New Indian Express, the USFDA has given the compound an ‘orphan drug’ designation, which helps in the development and evaluation of new treatments for rare diseases. It will also help fast-track the drug’s approval.
  • RGCB senior scientist Dr Ruby John Anto, along with her student Dr Lekshmi R Nath isolated the drug molecule — Uttroside-B — from the leaves of Manathakkali plant.

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