What is Amyloidosi?

A message from the family of former Pakistan President Pervez Musharraf said that his organs are malfunctioning, adding that “recovery is not possible”.

  • Has been hospitalized for the last 3 weeks due to a complication of his ailment (Amyloidosis).

What is Amyloidosis?

  • Amyloidosis is a rare disease that occurs when an abnormal protein, called amyloid, builds up in one’s organs, affecting their shape and functioning.
  • Amyloid deposits can build up in the heart, brain, kidneys, spleen and other parts of the body, leading to life-threatening conditions like organ failure.
  • Amyloid isn’t normally found in the body, but can be formed from several different types of proteins.
  • Some varieties of amyloidosis occur in association with other diseases. These types may improve with treatment of the underlying disease.
  • Some varieties of amyloidosis may lead to life-threatening organ failure.
  • Amyloidosis may be secondary to a different health condition or can develop as a primary condition as well.
  • Sometimes, it is due to a mutation in a gene, but usually, the cause of amyloidosis remains unknown.
  • Light-chain (AL) amyloidosis is the most common type in developed countries which can affect the kidneys, spleen, heart, and other organs.
  • Symptoms of amyloidosis are often subtle and can vary greatly depending on where the amyloid protein is collecting in the body.
  • As amyloidosis progresses, the deposits of amyloid can harm the heart, liver, spleen, kidneys, digestive tract, brain or nerves.

(Source: Indian Express)

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