Twigstats: An Advance Tool for Ancient DNA Analysis

Researchers have introduced Twigstats, an advanced ancient DNA analysis tool to uncover waves of human migration across Europe during the first millennium AD.

About Twigstats

  • Developed By: Researchers led by the Francis Crick Institute.
  • Purpose: Enhances the analysis of ancient DNA (aDNA) to track human migration patterns, especially in populations with closely related genetic traits.
  • Core Innovation:
    • Uses time-stratified ancestry analysis to significantly boost statistical power and reduce errors in measuring genetic differences.
    • Provides individual-level ancestry determination at unprecedented resolution.

Key Findings:

  • Application:
    • Analyzed 1,556 ancient DNA samples from individuals in northern and central Europe spanning 500 BC to 1000 AD (Iron, Roman, and Viking ages).
    • Revisited and refined ancestry data for population groups on the western frontiers of the Roman Empire during the first millennium AD.
  • Discoveries:
    • Generated high-resolution maps of migrations, including evidence of Germanic language speakers with Scandinavian-like ancestry spreading across Europe in the first century AD.
  • Validation:
    • Tested Twigstats on simulated genetic conditions and previous research to confirm robustness.

(Source: Science Daily)

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