Researchers of the Institute of Advanced Study in Science and Technology (IASST) in Guwahati have discovered a specific protein IL-35.
- It protects the immune system by lowering particular immune cells that produce inflammatory chemicals, thereby reducing pancreatic cell infiltration, a key contributor in type 1 diabetes and autoimmune diabetes mellitus.
- This protein presents a novel diabetes treatment option. The growing global diabetes epidemic that disproportionately affects developing country children and adolescents calls for effective treatment for the disease.
- IL-35, a specific protein of IL-12α and IL-27β chains, encoded by the IL12A and EBI3 genes.
- This finding has piqued scientists’ interest, especially considering the Novel type 1 and autoimmune diabetes therapy may depend on IL-35, according to research.
- IL-35 helps protect against type 1 and autoimmune diabetes.
- It regulates macrophage activation, T-cell proteins, and regulatory B cells. IL-35 inhibited pancreatic beta cell-attacking immune cells.
- Additionally, IL-35 lowered particular immune cells that produce inflammatory chemicals, reducing pancreatic cell infiltration, a key contributor in type 1 diabetes and autoimmune diabetes mellitus.
