Olfactory system and loss of smell during Covid-19

A new study Published in Scientific Reports has shed light on apparent brain changes or neurological consequences of COVID-19, especially in those who lost their sense of smell post-diagnosis.

Key points

  • The study found that those with anosmia (the loss of smell) during Covid-19 showed alterations in brain functionality and even physical structure during recovery.
  • Loss of smell in Covid-19 occurs due to the virus’ impact on the olfactory system in the nasal passages.
  • Specifically, the SARS-CoV-2 virus targets cells in the upper part of the nasal cavity, where the olfactory neurons are located. These neurons are responsible for detecting smells and sending signals to the brain.
  • The virus infects supporting cells around the olfactory neurons, causing inflammation and disruption of normal function.
  • This inflammation can lead to a blockage of the nasal passages or direct damage to the cells that help detect smells, resulting in temporary or prolonged loss of smell.
  • Covid-19‘s direct impact on the olfactory system often leads to a more pronounced and sometimes longer-lasting loss of smell, even in the absence of nasal congestion.

(Source: IE)

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