Nobel Prize in Chemistry 2022: Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless awarded for click chemistry

The Nobel Prize in chemistry for 2022 was awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for developing “an ingenious tool for building molecule”.

  • The three researchers were awarded for the development of click chemistry and bioorthogonal chemistry.

Key points

  • Barry Sharpless and Morten Meldal have laid the foundation for a functional form of chemistry – click chemistry – in which molecular building blocks snap together quickly and efficiently.
  • Carolyn Bertozzi has taken click chemistry to a new dimension and started utilising it in living organisms. Her bioorthogonal reactions take place without disrupting the normal chemistry of the cell.
  • Barry Sharpless and Morten Meldal have laid the foundation for a functional form of chemistry – click chemistry – in which molecular building blocks snap together quickly and efficiently.
  • The Nobel Prize in Chemistry 2022 is about making difficult processes easier.
  • Click chemistry and bioorthogonal reactions have taken chemistry into the era of functionalism.
  • Click chemistry is utilised in the development of pharmaceuticals, for mapping DNA and creating materials that are more fit for purpose.
  • Using bioorthogonal reactions, researchers have improved the targeting of cancer pharmaceuticals.

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