The Nobel Prize in chemistry for 2022 was awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for developing “an ingenious tool for building molecule”.
- The three researchers were awarded for the development of click chemistry and bioorthogonal chemistry.
Key points
- Barry Sharpless and Morten Meldal have laid the foundation for a functional form of chemistry – click chemistry – in which molecular building blocks snap together quickly and efficiently.
- Carolyn Bertozzi has taken click chemistry to a new dimension and started utilising it in living organisms. Her bioorthogonal reactions take place without disrupting the normal chemistry of the cell.
- Barry Sharpless and Morten Meldal have laid the foundation for a functional form of chemistry – click chemistry – in which molecular building blocks snap together quickly and efficiently.
- The Nobel Prize in Chemistry 2022 is about making difficult processes easier.
- Click chemistry and bioorthogonal reactions have taken chemistry into the era of functionalism.
- Click chemistry is utilised in the development of pharmaceuticals, for mapping DNA and creating materials that are more fit for purpose.
- Using bioorthogonal reactions, researchers have improved the targeting of cancer pharmaceuticals.