A research group from physical sciences division of the Institute of Advanced Study in Science and Technology, Guwahati has fabricated monolayers of pure myelin basic protein (MBP).
Key points
- MBP is a major protein component of myelin sheath.
- Researchers used a technique called the Langmuir-Blodgett (LB) technique to form monolayers of pure myelin basic protein at the air-water and air-solid interfaces.
- MBP is a protective membrane that wraps around the axon of nerve cells and acts as a model protein in studying diseases like multiple sclerosis (MS).
- MBP helps in compactification of the myelin sheath, and the fabricated tailored monolayers can give an in-depth understanding of the role of MBP in forming multi-lamellar myelin sheath structure as well as preserving the integrity, stability, and compactness of the sheath.
