A recent study published in the journal “American Chemical Society Pharmacology and Translational Science” found that mangoes are useful in protecting the gut health and protect people from several gastro disorders.
- The researchers demonstrated that mangiferin protects animals from experimentally induced colitis, a form of inflammatory bowel disease (IBD). Mangoes are one of the most favourite fruits in the country.
- Estimated to be over 5,000 years old, the Indo-Burmese origin fruit comes with Vitamins A, B6 and C.
Mangiferin
- Mangiferin is a natural compound classified as a xanthone glycoside, which is found in various plants, including the mango tree (Mangifera indica), from which it derives its name.
- The study found that mangiferin is found to have prevented mucosal erosion and infiltration of inflammatory cells, which were induced by acetic acid, in animals.
- The study also demonstrated anti-cancer properties of mangiferin on colon cancer cell line, Caco-2 by increasing the expression of pro-apoptotic markers.
Inflammatory bowel disease (IBD)
- Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract.
- The incidence of IBD has almost doubled in India from 1990 to 2019 as a result of changes in dietary habits and lifestyle.
- A prolonged IBD condition, if not treated, may result in the damage of the GI tract and lead to cancers. “
