Biological E’s Corbevax vaccine

Government of India has placed an advance order to block 300 million doses of a new Covid-19 vaccine, Corbevax, from Hyderabad-based company Biological E.

  • Corbevax is a “recombinant protein sub-unit” vaccine, which means it is made up of a specific part of SARS-CoV-2 — the spike protein on the virus’s surface.
  • The spike protein allows the virus to enter the cells in the body so that it can replicate and cause disease.
  • However, when this protein alone is given to the body, it is not expected to be harmful as the rest of the virus is absent.
  • The body is expected to develop an immune response against the injected spike protein.
  • Therefore, when the real virus attempts to infect the body, it will already have an immune response ready that will make it unlikely for the person to fall severely ill.
  • This technology has been used for decades to make hepatitis B vaccines, Corbevax will be among the first Covid-19 vaccines to use this platform.

(Source: Indian Express)

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