Clade 1b: WHO declares mpox a public health emergency of international concern (PHEIC)

WHO Director-General has determined that the upsurge of mpox in the Democratic Republic of the Congo (DRC) and a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the International Health Regulations (2005) (IHR).

  • This PHEIC determination is the second in two years relating to mpox. Caused by an Orthopoxvirus, mpox was first detected in humans in 1970, in the DRC.
  • The disease is considered endemic to countries in central and west Africa. In July 2022, the multi-country outbreak of mpox was declared a PHEIC as it spread rapidly via sexual contact across a range of countries where the virus had not been seen before.
  • That PHEIC was declared over in May 2023 after there had been a sustained decline in global cases.
  • As per, WHO, the emergence last year and rapid spread of a new virus strain in DRC, clade 1b, which appears to be spreading mainly through sexual networks, and its detection in countries neighbouring the DRC is especially concerning, and one of the main reasons for the declaration of the PHEIC.
  • A new type of Mpox called “clade 1b” appears to be deadlier and able to spread from person-to-person more easily than previous forms.
  • Mortality rates are as high as 10% of infections.
  • On 15 August 2024, Sweden became the first country outside the African continent to confirm mpox clade Ib in an individual with travel history to central Africa.

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